Variability of Platelet Reactivity on Antiplatelet Therapy in Neurointervention Procedure
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چکیده
منابع مشابه
The Emerging Role of miR-223 in Platelet Reactivity: Implications in Antiplatelet Therapy
Platelets are anuclear cells and are devoid of genomic DNA, but they are capable of de novo protein synthesis from mRNA derived from their progenitor cells, megakaryocytes. There is mounting evidence that microRNA (miRNA) plays an important role in regulating gene expression in platelets. miR-223 is the most abundant miRNAs in megakaryocytes and platelets. One of the miR-223-regulated genes is ...
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We read with great interest the report by Viviani Anselmi et al. (1) on the predictability of platelet reactivity as compared with gene polymorphism in patients undergoing elective percutaneous coronary intervention (PCI). The authors conclude that CYP2C19 metabolizer status independently predicts major adverse cardiac events, whereas platelet reactivity is only an independent predictor in high...
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Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and calcification of the vascular endothelium. Activated platelets in damaged blood vessels can trigger...
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ژورنال
عنوان ژورنال: Journal of Korean Neurosurgical Society
سال: 2019
ISSN: 2005-3711,1598-7876
DOI: 10.3340/jkns.2018.0151